Type 2 Diabetes
Approximately 28 million Americans have type 2 diabetes and this number is growing as there are 1.8 million new cases per year reported in the US alone.
Upon diagnosis, patients present with 50% reduction in pancreatic beta cell mass. More than half of theses patients become "insulin requiring" and then "insulin dependent". Current treatments work to help tissues become more sensitive to insulin that is available, or to wring out more insulin from existing tired cells, or to stop the liver from producing too much glucose. No existing treatments directly restore the underlying lost endocrine function of the pancreas.
HIP2B stimulates new islets to form in the pancreas to alleviate stress on existing cells and reverse the progression of type 2 diabetes.